Assessment of Intratumoral Doxorubicin Penetration after Mild Hyperthermia-Mediated Release from Thermosensitive Liposomes

In solid tumors, rapid local intravascular release of anticancer agents, e.g., doxorubicin (DOX), from thermosensitive liposomes (TSLs) can be an option to overcome poor extravasation of drug nanocarriers. The driving force of DOX penetration is the drug concentration gradient between the vascular c...

Full description

Bibliographic Details
Main Authors: Marc Derieppe, Jean-Michel Escoffre, Baudouin Denis de Senneville, Quincy van Houtum, Angelique Barten-van Rijbroek, Kim van der Wurff-Jacobs, Ludwig Dubois, Clemens Bos, Chrit Moonen
Format: Article
Language:English
Published: Hindawi-Wiley 2019-01-01
Series:Contrast Media & Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2019/2645928