Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities

Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities

A hyaluronic acid-grafted poly(<i>N</i>-isopropylacrylamide) (HA-pNIPAM) was synthesized as a polymeric nanogel platform for encapsulation and delivery of hydrophobic bioactive compounds using curcumin as a model drug. As demonstrated by transmission electron microscopy and dynamic light...

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Bibliographic Details
Main Authors: Jittima Amie Luckanagul, Pahweenvaj Ratnatilaka Na Bhuket, Chawanphat Muangnoi, Pranee Rojsitthisak, Qian Wang, Pornchai Rojsitthisak
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Polymers
Subjects:
curcumin
hyaluronic acid
HA-pNIPAM
thermoresponsive nanogel
Online Access:https://www.mdpi.com/2073-4360/13/2/194

Internet

https://www.mdpi.com/2073-4360/13/2/194

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