Improving the Predictions of Computational Models of Convection-Enhanced Drug Delivery by Accounting for Diffusion Non-gaussianity

Improving the Predictions of Computational Models of Convection-Enhanced Drug Delivery by Accounting for Diffusion Non-gaussianity

Convection-enhanced delivery (CED) is an innovative method of drug delivery to the human brain, that bypasses the blood-brain barrier by injecting the drug directly into the brain. CED aims to target pathological tissue for central nervous system conditions such as Parkinson's and Huntington�...

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Bibliographic Details
Main Authors: Eirini Messaritaki, Suryanarayana Umesh Rudrapatna, Greg D. Parker, William P. Gray, Derek K. Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
Subjects:
convection-enhanced drug delivery
diffusion MRI
non-Gaussian diffusion
neurodegenerative diseases
computational fluid dynamics
Parkinson's disease
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01092/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.01092/full

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