New therapeutic target for pediatric anaplastic ependymoma control: study of anti-tumor activity by a Kunitz-type molecule, Amblyomin-X

New therapeutic target for pediatric anaplastic ependymoma control: study of anti-tumor activity by a Kunitz-type molecule, Amblyomin-X

Abstract EPNs comprise a heterogeneous group of neuroepithelial tumors, accounting for about 10% of all intracranial tumors in children and up to 30% of brain tumors in those younger than 3 years. Actually, the pattern therapy for low-grade EPNs includes complete surgical resection followed by radia...

Full description

Bibliographic Details
Main Authors: Lorena Favaro Pavon, David Capper, Tatiana Tais Sibov, Silvia Regina Caminada de Toledo, Ulrich-W. Thomale, Jean Gabriel de Souza, Francisco Romero Cabral, Carolina Maria Berra, Marcos Devanir Silva da Costa, Jardel Mendonça Niçacio, Patrícia Alessandra Dastoli, Daniela Mara de Oliveira, Suzana M. F. Malheiros, Edgar Ferreira da Cruz, Jackeline Moraes Malheiros, Sérgio Mascarenhas de Oliveira, Nasjla Saba Silva, Antonio Sérgio Petrilli, Andrea Maria Cappellano, Milena Colò Brunialti, Reinaldo Salomão, Manoel A. de Paiva Neto, Ana Marisa Chudzinski-Tavassi, Sérgio Cavalheiro
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-45799-4

Internet

https://doi.org/10.1038/s41598-019-45799-4

Similar Items