Covalent Binding of Heparin to Functionalized PET Materials for Improved Haemocompatibility

Covalent Binding of Heparin to Functionalized PET Materials for Improved Haemocompatibility

The hemocompatibility of vascular grafts made from poly(ethylene terephthalate) (PET) is insufficient due to the rapid adhesion and activation of blood platelets that occur upon incubation with whole blood. PET polymer was treated with NHx radicals created by passing ammonia through gaseous plasma f...

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Bibliographic Details
Main Authors: Metod Kolar, Miran Mozetič, Karin Stana-Kleinschek, Mirjam Fröhlich, Boris Turk, Alenka Vesel
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Materials
Subjects:
poly(ethylene terephthalate)
vascular graft
biocompatibility
heparin
plasma
functionalization
haemolysis
platelet adhesion
endothelization
Online Access:http://www.mdpi.com/1996-1944/8/4/1526

Internet

http://www.mdpi.com/1996-1944/8/4/1526

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