Synthesis and Determination of pKa Values of Some New 3,4-Disubstituted-4,5-Dihydro-1H-1,2,4-triazol-5-one Derivatives in Non-aqueous Solvents

Synthesis and Determination of pKa Values of Some New 3,4-Disubstituted-4,5-Dihydro-1H-1,2,4-triazol-5-one Derivatives in Non-aqueous Solvents

3-Alkyl(Aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) reacted with 2-furoyl chloride and thiophene-2-carbonyl chloride to afford the corresponding 3- alkyl(aryl)-4-(2-furoylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) and 3-alkyl(aryl)- 4-(2-thienylcarbonylamino)-4,5-dihydro-1H-1,2,4-triaz...

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Bibliographic Details
Main Authors: Mustafa Özdemir, Sule Bahçeci, Muzaffer Alkan, Zafer Ocak, Haydar Yüksek
Format: Article
Language:English
Published: MDPI AG 2004-03-01
Series:Molecules
Subjects:
4
5-Dihydro-1H-1
2
4-triazol-5-ones
acylation
acidity
potentiometric titration
syntheses.
Online Access:http://www.mdpi.com/1420-3049/9/4/232/

Internet

http://www.mdpi.com/1420-3049/9/4/232/

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