Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease

Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease

Aspartic proteases are common in eukaryotes and retroviruses but are relatively rare among bacteria (N. D. Rawlings and A. Bateman, BMC Genomics 10:437, 2009, https://doi.org/10.1186/1471-2164-10-437). In contrast to eukaryotic aspartic proteases, bacterial aspartic proteases are generally located i...

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Bibliographic Details
Main Authors: Maroeska J. Burggraaf, Alexander Speer, Aniek S. Meijers, Roy Ummels, Astrid M. van der Sar, Konstantin V. Korotkov, Wilbert Bitter, Coenraad Kuijl
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mBio
Subjects:
aspartic protease
mycobacterium
pe proteins
pe_pgrs
type vii secretion
Online Access:https://doi.org/10.1128/mBio.01951-19

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