Comparative genomics of Bordetella pertussis reveals progressive gene loss in Finnish strains.

BACKGROUND: Bordetella pertussis is a gram-negative bacterium that infects the human respiratory tract and causes pertussis or whooping cough. The disease has resurged in many countries including Finland where the whole-cell pertussis vaccine has been used for more than 50 years. Antigenic divergenc...

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Bibliographic Details
Main Authors: Eriikka Heikkinen, Teemu Kallonen, Lilli Saarinen, Rolf Sara, Audrey J King, Frits R Mooi, Juhani T Soini, Jussi Mertsola, Qiushui He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1975675?pdf=render