FRET-Based Detection and Quantification of HIV-1 Virion Maturation

FRET-Based Detection and Quantification of HIV-1 Virion Maturation

HIV-1 infectivity is achieved through virion maturation. Virus particles undergo structural changes via cleavage of the Gag polyprotein mediated by the viral protease, causing the transition from an uninfectious to an infectious status. The majority of proviruses in people living with HIV-1 treated...

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Bibliographic Details
Main Authors: Anamaria D. Sarca, Luca Sardo, Hirofumi Fukuda, Hiroyuki Matsui, Kotaro Shirakawa, Kazuki Horikawa, Akifumi Takaori-Kondo, Taisuke Izumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Microbiology
Subjects:
HIV-1 Gag maturation
Förster Resonance Energy Transfer
single virion imaging
protease inhibitor
fluorescence microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.647452/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.647452/full

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