An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function

An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function

Abstract The release of neuropeptides from dense core vesicles (DCVs) modulates neuronal activity and plays a critical role in cognitive function and emotion. The granin family is considered a master regulator of DCV biogenesis and the release of DCV cargo molecules. The expression of the VGF protei...

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Bibliographic Details
Main Authors: Wei-Jye Lin, Yan Zhao, Zhe Li, Shuyu Zheng, Jin-lin Zou, Noël A. Warren, Purva Bali, Jingru Wu, Mengdan Xing, Cheng Jiang, Yamei Tang, Stephen R. Salton, Xiaojing Ye
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01489-2

Internet

https://doi.org/10.1038/s41398-021-01489-2

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