Xenofree generation of limbal stem cells for ocular surface advanced cell therapy

Abstract Background Limbal stem cells (LSC) sustain the corneal integrity and homeostasis. LSC deficiency (LSCD) leads to loss of corneal transparency and blindness. A clinical approach to treat unilateral LSCD comprises autologous cultured limbal epithelial stem cell transplantation (CLET). CLET us...

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Bibliographic Details
Main Authors: Nuria Nieto-Nicolau, Eva M. Martínez-Conesa, Alba M. Velasco-García, Caterina Aloy-Reverté, Anna Vilarrodona, Ricardo P. Casaroli-Marano
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Stem Cell Research & Therapy
Subjects:
3T3
Online Access:https://doi.org/10.1186/s13287-019-1501-9