Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis.

Long-term supplementation with branched-chain amino acids (BCAA) is associated with prolonged survival and decreased frequency of development of hepatocellular carcinoma (HCC) in patients with liver cirrhosis. However, the pharmaceutical mechanism underlying this association is still unclear. We inv...

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Bibliographic Details
Main Authors: Motoh Iwasa, Yoshinao Kobayashi, Rumi Mifuji-Moroka, Nagisa Hara, Hirohide Miyachi, Ryosuke Sugimoto, Hideaki Tanaka, Naoki Fujita, Esteban C Gabazza, Yoshiyuki Takei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3723692?pdf=render