Cohesin rings devoid of Scc3 and Pds5 maintain their stable association with the DNA.

Cohesin is a protein complex that forms a ring around sister chromatids thus holding them together. The ring is composed of three proteins: Smc1, Smc3 and Scc1. The roles of three additional proteins that associate with the ring, Scc3, Pds5 and Wpl1, are not well understood. It has been proposed tha...

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Bibliographic Details
Main Authors: Irina Kulemzina, Martin R Schumacher, Vikash Verma, Jochen Reiter, Janina Metzler, Antonio Virgilio Failla, Christa Lanz, Vipin T Sreedharan, Gunnar Rätsch, Dmitri Ivanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3415457?pdf=render