Cudarflavone B Provides Neuroprotection against Glutamate-Induced Mouse Hippocampal HT22 Cell Damage through the Nrf2 and PI3K/Akt Signaling Pathways

Cudarflavone B Provides Neuroprotection against Glutamate-Induced Mouse Hippocampal HT22 Cell Damage through the Nrf2 and PI3K/Akt Signaling Pathways

Oxidative cell damage contributes to neuronal degeneration in many central nervous system (CNS) diseases such as Alzheimer’s disease, Parkinson’s disease, and ischemia. Nrf2 signaling-mediated heme oxygenase (HO)-1 expression acts against oxidants that are thought to play a key role in the pathogene...

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Bibliographic Details
Main Authors: Dong-Sung Lee, Wonmin Ko, Dong-Cheol Kim, Youn-Chul Kim, Gil-Saeng Jeong
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
cudraflavone B
glutamate
oxidative stress
neuroprotection
mouse hippocampal HT22
nuclear factor-E2-related factor 2
heme oxygenase-1
Online Access:http://www.mdpi.com/1420-3049/19/8/10818

Internet

http://www.mdpi.com/1420-3049/19/8/10818

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