Mechanism of Methylprednisolone‐Induced Primary Cilia Formation Disorder and Autophagy in Osteoblasts

Objective To study the role of primary cilia formation disorder and osteoblasts autophagy in the pathogenesis of steroid‐induced avascular necrosis of the femoral head (SANFH). Methods Osteoblasts were isolated from rabbit bones and treated with 1 μM Methylprednisolone for 0, 12, 24, 48, and 72 h. T...

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Bibliographic Details
Main Authors: Zhen‐qun Zhao, Wan‐lin Liu, Shi‐bing Guo, Rui Bai, Jing‐long Yan
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Orthopaedic Surgery
Subjects:
Online Access:https://doi.org/10.1111/os.12630