Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers

Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers

Nucleated teleost red blood cells (RBCs) are known to express molecules from the major histocompatibility complex and peptide-generating processes such as autophagy and proteasomes, but the role of RBCs in antigen presentation of viruses have not been studied yet. In this study, RBCs exposed ex vivo...

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Bibliographic Details
Main Authors: Ivan Nombela, Ricardo Requena-Platek, Byron Morales-Lange, Veronica Chico, Sara Puente-Marin, Sergio Ciordia, Maria Carmen Mena, Julio Coll, Luis Perez, Luis Mercado, Maria del Mar Ortega-Villaizan
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
rainbow trout
erythrocytes
red blood cells
VHSV
transcriptome
proteome
antigen presentation
autophagy
ubiquitination
Online Access:https://www.mdpi.com/2073-4409/8/5/386

Internet

https://www.mdpi.com/2073-4409/8/5/386

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