Analyzing the 3D chromatin organization coordinating with gene expression regulation in B-cell lymphoma

Analyzing the 3D chromatin organization coordinating with gene expression regulation in B-cell lymphoma

Abstract Background Eukaryotes compact chromosomes densely and non-randomly, forming three-dimensional structures. Alterations of the chromatin structures are often associated with diseases. In particular, aggressive cancer development from the disruption of the humoral immune system presents abnorm...

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Bibliographic Details
Main Authors: Luis Augusto Eijy Nagai, Sung-Joon Park, Kenta Nakai
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Medical Genomics
Subjects:
Chromatin organization
Transcriptome
Lymphoma
B cell
Hi-C
Online Access:http://link.springer.com/article/10.1186/s12920-018-0437-8

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http://link.springer.com/article/10.1186/s12920-018-0437-8

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