Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells

Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells

Efferent cholinergic neurons inhibit sensory hair cells of the vertebrate inner ear through the combined action of calcium-permeable α9α10-containing nicotinic acetylcholine receptors (nAChRs) and associated calcium-dependent potassium channels. The venom of cone snails is a rich repository of bioac...

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Bibliographic Details
Main Authors: Fernando Fisher, Yuanyuan Zhang, Philippe F. Y. Vincent, Joanna Gajewiak, Thomas J. Gordon, Elisabeth Glowatzki, Paul Albert Fuchs, J. Michael McIntosh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
conotoxin
nAChR
cochlea
mouse
Xenopus
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.697560/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.697560/full

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