The Epithelial-Mesenchymal Transcription Factor Slug Predicts Survival Benefit of Up-Front Surgery in Head and Neck Cancer
EMT promotes radio- and chemotherapy resistance in HNSCC in vitro. As EMT has been correlated to the transcription factor Slug in tumor specimens from HNSCC patients, we assessed whether Slug overexpression predicts radio- and chemotherapy resistance and favors upfront surgery in HNSCC patients. Slu...
Main Authors: | Herbert Riechelmann, Teresa Bernadette Steinbichler, Susanne Sprung, Matthias Santer, Annette Runge, Ute Ganswindt, Gabriele Gamerith, Jozsef Dudas |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/4/772 |
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