Computational Elucidation of Structural Basis for Ligand Binding with Leishmania donovani Adenosine Kinase

Enzyme adenosine kinase is responsible for phosphorylation of adenosine to AMP and is crucial for parasites which are purine auxotrophs. The present study describes development of robust homology model of Leishmania donovani adenosine kinase to forecast interaction phenomenon with inhibitory molecul...

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Bibliographic Details
Main Authors: Rajiv K. Kar, Md. Yousuf Ansari, Priyanka Suryadevara, Bikash R. Sahoo, Ganesh C. Sahoo, Manas R. Dikhit, Pradeep Das
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/609289