Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice

Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice

The pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) is not fully understood, but evidence is accumulating that immune dysfunction plays a significant role. We previously reported that 31-week-old <i>Tnfaip3<sup>DNGR1-KO</sup></i> mice develop pulmonary hyper...

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Bibliographic Details
Main Authors: Denise van Uden, Thomas Koudstaal, Jennifer A. C. van Hulst, Ingrid M. Bergen, Chelsea Gootjes, Nicholas W. Morrell, Geert van Loo, Jan H. von der Thüsen, Thierry P. P. van den Bosch, Maria-Rosa Ghigna, Frédéric Perros, David Montani, Mirjam Kool, Karin A. Boomars, Rudi W. Hendriks
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
pulmonary arterial hypertension
dendritic cells
inflammation
<i>Tnfaip3</i>
BMPR2
Toll-like receptor
Online Access:https://www.mdpi.com/1422-0067/22/4/1756

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https://www.mdpi.com/1422-0067/22/4/1756

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