Loss of cholecystokinin-containing terminals in temporal lobe epilepsy

Altered GABA-mediated inhibition is proposed to play a role in the pathogenesis of epilepsy. Previous studies have demonstrated a loss of somatostatin-containing GABAergic interneurons innervating granule cells in epileptic animals. However, the reorganization of synapses between interneurons and gr...

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Bibliographic Details
Main Authors: Chengsan Sun, Jianli Sun, Alev Erisir, Jaideep Kapur
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113002520