Stable Redox-Cycling Nitroxide Tempol Has Antifungal and Immune-Modulatory Properties

Stable Redox-Cycling Nitroxide Tempol Has Antifungal and Immune-Modulatory Properties

Invasive mycoses remain underdiagnosed and difficult to treat. Hospitalized individuals with compromised immunity increase in number and constitute the main risk group for severe fungal infections. Current antifungal therapy is hampered by slow and insensitive diagnostics and frequent toxic side eff...

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Bibliographic Details
Main Authors: Ava Hosseinzadeh, Marios Stylianou, José Pedro Lopes, Daniel C. Müller, André Häggman, Sandra Holmberg, Christian Grumaz, Anders Johansson, Kai Sohn, Christoph Dieterich, Constantin F. Urban
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
antifungal activity
redox active
immunomodulators
candidiasis
Candida albicans
Candida glabrata
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01843/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01843/full

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