Two Toxic Lipid Aldehydes, 4-hydroxy-2-hexenal (4-HHE) and 4-hydroxy-2-nonenal (4-HNE), Accumulate in Patients with Chronic Kidney Disease

Lipid aldehydes originating from the peroxidation of n-3 and n-6 polyunsaturated fatty acids are increased in hemodialysis (HD) patients, a process already known to promote oxidative stress. However, data are lacking for patients with chronic kidney disease (CKD) before the initiation of HD. We pros...

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Bibliographic Details
Main Authors: Christophe O. Soulage, Caroline C. Pelletier, Nans Florens, Sandrine Lemoine, Laurence Dubourg, Laurent Juillard, Fitsum Guebre-Egziabher
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/9/567