Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer.

Genome wide association studies (GWAS) have identified several SNPs associated with colorectal cancer (CRC) susceptibility. Vitamin D is also inversely associated with CRC risk.We examined main and joint effects of previously GWAS identified genetic markers of CRC and plasma 25-hydroxyvitamin D (25(...

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Bibliographic Details
Main Authors: Linda T Hiraki, Amit D Joshi, Kimmie Ng, Charles S Fuchs, Jing Ma, Aditi Hazra, Ulrike Peters, Elizabeth W Karlson, Edward Giovannucci, Peter Kraft, Andrew T Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3966783?pdf=render