Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study

Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study

Context: Post-finasteride syndrome (PFS) occurs in patients with androgenic alopecia after suspension of the finasteride treatment, leading to a large variety of persistent side effects. Despite the severity of the clinical picture, the mechanism underlying the PFS symptoms onset and persistence is...

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Bibliographic Details
Main Authors: Roberto Cosimo Melcangi, Livio Casarini, Marco Marino, Daniele Santi, Samantha Sperduti, Silvia Giatti, Silvia Diviccaro, Maria Grimoldi, Donatella Caruso, Guido Cavaletti, Manuela Simoni
Format: Article
Language:English
Published: Bioscientifica 2019-07-01
Series:Endocrine Connections
Subjects:
5 alpha-reductase
neuroactive steroids
finasteride
side effects
epigenetic changes
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/8/EC-19-0199.xml

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https://ec.bioscientifica.com/view/journals/ec/8/8/EC-19-0199.xml

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