Anti-apoptotic signature in thymic squamous cell carcinomas - functional relevance of anti-apoptotic BIRC3 expression in the thymic carcinoma cell line 1889c

Anti-apoptotic signature in thymic squamous cell carcinomas - functional relevance of anti-apoptotic BIRC3 expression in the thymic carcinoma cell line 1889c

The molecular pathogenesis of thymomas and thymic carcinomas (TCs) is poorly understood and results of adjuvant therapy are unsatisfactory in case of metastatic disease and tumor recurrence. For these clinical settings, novel therapeutic strategies are urgently needed. Recently, limited sequencing e...

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Bibliographic Details
Main Authors: Bei eHuang, Djeda eBelharazem, Li eLi, Susanne eKneitz, Philipp eSchnabel, Ralf eRieker, Daniel eKörner, Winnfried eNix, Berthold eSchalke, Hans Konrad eMüller-Hermelink, German eOtt, Andreas eRosenwald, Philipp eStröbel, Alexander eMarx
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Gene Expression
Myasthenia Gravis
Thymoma
targeted therapy
Thymus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00316/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00316/full

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