CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

Recently, several promising treatments for high-grade gliomas (HGGs) failed to provide significant benefit when translated from the preclinical setting to patients. Improving the animal models is fundamental to overcoming this translational gap. To address this need, we developed and comprehensively...

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Bibliographic Details
Main Authors: Matteo Riva, Roxanne Wouters, Akila Weerasekera, Sarah Belderbos, David Nittner, Dietmar R. Thal, Thaïs Baert, Roberto Giovannoni, Willy Gsell, Uwe Himmelreich, Marc Van Ranst, An Coosemans
Format: Article
Language:English
Published: The Company of Biologists 2019-09-01
Series:Biology Open
Subjects:
High-grade glioma model
CT-2A
Glioma stem cells
Immunosuppression
Tregs
Online Access:http://bio.biologists.org/content/8/9/bio044552

Internet

http://bio.biologists.org/content/8/9/bio044552

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