CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression
Recently, several promising treatments for high-grade gliomas (HGGs) failed to provide significant benefit when translated from the preclinical setting to patients. Improving the animal models is fundamental to overcoming this translational gap. To address this need, we developed and comprehensively...
Main Authors: | Matteo Riva, Roxanne Wouters, Akila Weerasekera, Sarah Belderbos, David Nittner, Dietmar R. Thal, Thaïs Baert, Roberto Giovannoni, Willy Gsell, Uwe Himmelreich, Marc Van Ranst, An Coosemans |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-09-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/8/9/bio044552 |
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