Short-Term Strength Exercise Reduces Hepatic Insulin Resistance in Obese Mice by Reducing PTP1B Content, Regardless of Changes in Body Weight

Short-Term Strength Exercise Reduces Hepatic Insulin Resistance in Obese Mice by Reducing PTP1B Content, Regardless of Changes in Body Weight

Obesity is closely related to insulin resistance and type 2 diabetes genesis. The liver is a key organ to glucose homeostasis since insulin resistance in this organ increases hepatic glucose production (HGP) and fasting hyperglycemia. The protein-tyrosine phosphatase 1B (PTP1B) may dephosphorylate t...

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Bibliographic Details
Main Authors: Kellen Cristina da Cruz Rodrigues, Rodrigo Martins Pereira, Guilherme Francisco Peruca, Lucas Wesley Torres Barbosa, Marcella Ramos Sant’Ana, Vitor Rosetto Muñoz, Ana Paula Morelli, Fernando Moreira Simabuco, Adelino Sanchez Ramos da Silva, Dennys Esper Cintra, Eduardo Rochete Ropelle, José Rodrigo Pauli, Leandro Pereira de Moura
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
strength exercise
obesity
liver
insulin signaling
diabetes
PTP1B
Online Access:https://www.mdpi.com/1422-0067/22/12/6402

Internet

https://www.mdpi.com/1422-0067/22/12/6402

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