In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases

In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases

Cytochromes c are ubiquitous heme proteins in mitochondria and bacteria, all possessing a CXXCH (CysXxxXxxCysHis) motif with covalently attached heme. We describe the first in vitro reconstitution of cytochrome c biogenesis using purified mitochondrial (HCCS) and bacterial (CcsBA) cytochrome c synth...

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Bibliographic Details
Main Authors: Molly C Sutherland, Deanna L Mendez, Shalon E Babbitt, Dustin E Tillman, Olga Melnikov, Nathan L Tran, Noah T Prizant, Andrea L Collier, Robert G Kranz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
Heme
cytochrome c
synthases
heme attachment
cytochrome c biogenesis
post translational modification
Online Access:https://elifesciences.org/articles/64891

Internet

https://elifesciences.org/articles/64891

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