New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis

New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis

Abstract Osteoarthritis (OA) is the most common joint disorder and affects approximately half of the aged population. Current treatments for OA are largely palliative until the articular cartilage has been deeply damaged and irreversible morphological changes appear. Thus, effective methods are need...

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Bibliographic Details
Main Authors: Heng Li, Dan Wang, Yongjian Yuan, Jikang Min
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Arthritis Research & Therapy
Subjects:
Matrix metalloproteinases
MMP-13
Osteoarthritis
Non-coding RNA
DNA methylation
Autophagy
Online Access:http://link.springer.com/article/10.1186/s13075-017-1454-2

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http://link.springer.com/article/10.1186/s13075-017-1454-2

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