Mannan Enhances IL-12 Production by Increasing Bacterial Uptake and Endosomal Degradation in L. acidophilus and S. aureus Stimulated Dendritic Cells

Mannan Enhances IL-12 Production by Increasing Bacterial Uptake and Endosomal Degradation in L. acidophilus and S. aureus Stimulated Dendritic Cells

The mannose receptor (MR) is a C-type lectin involved in endocytosis and with a poorly defined ability to modulate cellular activation. We investigated the effect of mannan treatment prior to stimulation of murine bone marrow-derived dendritic cells with the Gram-positive bacteria Lactobacillus acid...

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Bibliographic Details
Main Authors: Ronja Mathiesen, Helene M. S. Eld, Juliane Sørensen, Eva Fuglsang, Lisbeth Drozd Lund, Valentina Taverniti, Hanne Frøkiær
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
Gram-positive bacteria
mannose receptor
IL-12
endosomal killing
phagocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02646/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02646/full

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