The Multiple Roles of B Cells in the Pathogenesis of Sjögren’s Syndrome

Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease characterized by lymphocytic infiltration and tissue destruction of exocrine glands such as salivary glands. Although the formation of ectopic lymphoid tissue in exocrine glands and overproduction of autoantibodies by autoreactive B ce...

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Bibliographic Details
Main Authors: Wenhan Du, Man Han, Xiaoxia Zhu, Fan Xiao, Enyu Huang, Nan Che, Xiaopo Tang, Hejian Zou, Quan Jiang, Liwei Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684999/full