Effects of Tumor Necrosis Factor-α on Morphology and Mechanical Properties of HCT116 Human Colon Cancer Cells Investigated by Atomic Force Microscopy

Chronic inflammation orchestrates the tumor microenvironment and is strongly associated with cancer. Tumor necrosis factor-α (TNFα) is involved in tumor invasion and metastasis by inducing epithelial to mesenchymal transition (EMT). This process is defined by the loss of epithelial characteristics a...

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Bibliographic Details
Main Authors: Huiqing Liu, Nan Wang, Zhe Zhang, Hongda Wang, Jun Du, Jilin Tang
Format: Article
Language:English
Published: Hindawi-Wiley 2017-01-01
Series:Scanning
Online Access:http://dx.doi.org/10.1155/2017/2027079