Association of aryl hydrocarbon receptor-related gene variants with the severity of autism spectrum disorders

Association of aryl hydrocarbon receptor-related gene variants with the severity of autism spectrum disorders

Exposure to environmental chemicals, such as dioxin, is known to have adverse effects on the homeostasis of gonadal steroids, thereby potentially altering the sexual differentiation of the brain to express autistic traits. Dioxin-like chemicals act on the aryl hydrocarbon receptor (AhR), polymorphis...

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Bibliographic Details
Main Authors: Takashi X. Fujisawa, Shota Nishitani, Ryoichiro Iwanaga, Junko Matsuzaki, Chisato Kawasaki, Mamoru Tochigi, Tsukasa Sasaki, Nobumasa Kato, Kazuyuki Shinohara
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Psychiatry
Subjects:
Aryl Hydrocarbon Receptor Nuclear Translocator
Polymorphism, Single Nucleotide
Autism Spectrum Disorders
social communication
severity
Aryl hydrocarbon receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2016.00184/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2016.00184/full

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