Canonical Sonic Hedgehog Signaling in Early Lung Development

Canonical Sonic Hedgehog Signaling in Early Lung Development

The canonical hedgehog (HH) signaling pathway is of major importance during embryonic development. HH is a key regulatory morphogen of numerous cellular processes, namely, cell growth and survival, differentiation, migration, and tissue polarity. Overall, it is able to trigger tissue-specific respon...

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Bibliographic Details
Main Authors: Hugo Fernandes-Silva, Jorge Correia-Pinto, Rute Silva Moura
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Journal of Developmental Biology
Subjects:
Sonic Hedgehog (SHH)
lung development
endoderm specification
branching morphogenesis
signaling
transcriptional regulation
Online Access:http://www.mdpi.com/2221-3759/5/1/3

Internet

http://www.mdpi.com/2221-3759/5/1/3

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