Morphological Stages of Mitochondrial Vacuolar Degeneration in Phenylephrine-Stressed Cardiac Myocytes and in Animal Models and Human Heart Failure

Morphological Stages of Mitochondrial Vacuolar Degeneration in Phenylephrine-Stressed Cardiac Myocytes and in Animal Models and Human Heart Failure

<i>Background and objectives</i>: Derangements in mitochondrial integrity and function constitute an important pathophysiological feature in the pathogenesis of heart failure (HF) and play an important role in myocardial remodeling and systolic dysfunction. In systolic HF, we and others...

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Bibliographic Details
Main Author: Antoine H. Chaanine
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Medicina
Subjects:
heart failure
oxidative stress
mitochondria
dynamics
morphology
vacuolar degeneration
Online Access:https://www.mdpi.com/1010-660X/55/6/239

Internet

https://www.mdpi.com/1010-660X/55/6/239

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