New luciferin-based probe substrates for human CYP26A1

Activity of human CYP26A1 towards six proluciferin probe substrates and their ester derivatives was monitored. These included three monofluorobenzyl ether isomers and three five-membered heterocycles. Overall, luciferin substrates with a free acid group gave higher activities than the ester compound...

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Bibliographic Details
Main Authors: Shishir Sharma, Jingyao Liu, Xue Zhang, Sangeeta Shrestha Sharma, Erik J. Sorensen, Matthias Bureik
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301710