Hsp40s specify functions of Hsp104 and Hsp90 protein chaperone machines.

Hsp40s specify functions of Hsp104 and Hsp90 protein chaperone machines.

Hsp100 family chaperones of microorganisms and plants cooperate with the Hsp70/Hsp40/NEF system to resolubilize and reactivate stress-denatured proteins. In yeast this machinery also promotes propagation of prions by fragmenting prion polymers. We previously showed the bacterial Hsp100 machinery coo...

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Bibliographic Details
Main Authors: Michael Reidy, Ruchika Sharma, Shankar Shastry, Brittany-Lee Roberts, Ivan Albino-Flores, Sue Wickner, Daniel C Masison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4199505?pdf=render

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http://europepmc.org/articles/PMC4199505?pdf=render

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