Functional evaluation of DNA repair in human biopsies and their relation to other cellular biomarkers

Functional evaluation of DNA repair in human biopsies and their relation to other cellular biomarkers

Thousands of DNA lesions are estimated to occur in each cell every day and almost all are recognized and repaired. DNA repair is an essential system that prevents accumulation of mutations which can lead to serious cellular malfunctions. Phenotypic evaluation of DNA repair activity of individuals is...

Full description

Bibliographic Details
Main Authors: Jana eSlyskova, Sabine eLangie, Andrew eCollins, Pavel eVodicka
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Genetics
Subjects:
nucleotide excision repair
Base excision repair
Human solid tissue
Methodological report
in vitro comet-based DNA repair assay
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00116/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00116/full

Similar Items