BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis.

BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis.

The double bromodomain and extra-terminal domain (BET) proteins are critical epigenetic readers that bind to acetylated histones in chromatin and regulate transcriptional activity and modulate changes in chromatin structure and organization. The testis-specific BET member, BRDT, is essential for the...

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Bibliographic Details
Main Authors: Marcia Manterola, Taylor M Brown, Min Young Oh, Corey Garyn, Bryan J Gonzalez, Debra J Wolgemuth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5841650?pdf=render

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http://europepmc.org/articles/PMC5841650?pdf=render

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