MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis

MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis

Abstract Background The extensive involvement of microRNA (miRNA) in the pathophysiology of psoriasis is well documented. However, in order for this information to be useful in therapeutic manipulation of miRNA levels, it is essential that detailed functional mechanisms are elucidated. This study ai...

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Bibliographic Details
Main Authors: Yan Wu, Liu Liu, Chunxiang Bian, Qingchun Diao, Muhammad Farrukh Nisar, Xuemei Jiang, Jörg W. Bartsch, Maojiao Zhong, Xiangyu Hu, Julia Li Zhong
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cell Communication and Signaling
Subjects:
Psoriasis
Let-7b
IL-6
ERK1/2
Differentiation
Online Access:http://link.springer.com/article/10.1186/s12964-018-0271-9

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http://link.springer.com/article/10.1186/s12964-018-0271-9

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