Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7.

Branching morphogenesis is a critical step in the development of many epithelial organs. The phosphoinositide-3-kinase (PI3K) pathway has been identified as a central component of this process but the precise role has not been fully established. Herein we sought to determine the role of PI3K in muri...

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Bibliographic Details
Main Authors: Edward Carter, Gabriela Miron-Buchacra, Silvia Goldoni, Henry Danahay, John Westwick, Malcolm L Watson, David Tosh, Stephen G Ward
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4251986?pdf=render