Serological Investigation of the Collagen Degradation Profile of Patients with Chronic Obstructive Pulmonary Disease or Idiopathic Pulmonary Fibrosis

In both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), abnormally high collagen remodeling occurs within the lung tissue. Matrix metalloproteinase (MMP)-degraded type I, III, IV, V and VI collagen and a disintegrin and metalloproteinase with thrombospondin moti...

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Bibliographic Details
Main Authors: Diana J. Leeming, Jannie M. Sand, Mette J. Nielsen, Federica Genovese, Fernando J. Martinez, Cory M. Hogaboam, MeiLan K Han, Lloyd B. Klickstein, Morten A. Karsdal
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S9415