Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo
Abstract Background Endothelial injury is an early and enduring feature of cardiovascular disease. Inflammation and hypoxia may be responsible for this, and are often associated with the up-regulation of several transcriptional factors that include Hypoxia Inducible Factor-1 (HIF-1). Although it has...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s10020-018-0026-5 |