Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo

Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo

Abstract Background Endothelial injury is an early and enduring feature of cardiovascular disease. Inflammation and hypoxia may be responsible for this, and are often associated with the up-regulation of several transcriptional factors that include Hypoxia Inducible Factor-1 (HIF-1). Although it has...

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Bibliographic Details
Main Authors: Lamia Heikal, Pietro Ghezzi, Manuela Mengozzi, Gordon Ferns
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Molecular Medicine
Subjects:
HIF-1α
Injury
Endothelial cells
ELISA
Angioplasty
Online Access:http://link.springer.com/article/10.1186/s10020-018-0026-5

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http://link.springer.com/article/10.1186/s10020-018-0026-5

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