Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?

Chronic obstructive pulmonary disease (COPD) patients are at increased risk of developing nonsmall cell lung carcinoma, irrespective of their smoking history. Although the mechanisms behind this observation are not clear, established drivers of carcinogenesis in COPD include oxidative stress and sus...

Full description

Bibliographic Details
Main Authors: Francois Ng Kee Kwong, Andrew G. Nicholson, Celeste L. Harrison, Philip M. Hansbro, Ian M. Adcock, Kian Fan Chung
Format: Article
Language:English
Published: European Respiratory Society 2017-10-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/26/146/170040.full