Surface-exposed and soluble calreticulin: conflicting biomarkers for cancer prognosis

Increased exposure of calreticulin (CALR) on malignant cells is associated with therapy-relevant adaptive immune responses and superior therapeutic outcome in solid tumors and haemato-oncological diseases, because surface-exposed CALR acts as an ‘eat-me’ signal facilitating the phagocytosis of stres...

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Bibliographic Details
Main Authors: Oliver Kepp, Peng Liu, Liwei Zhao, Isabelle Plo, Guido Kroemer
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1792037