Methylglyoxal Inhibits Smooth Muscle Contraction in Isolated Blood Vessels

Methylglyoxal (MGO) is a metabolite of glucose. In addition to evidence that increased plasma MGO level is associated with diabetic vascular complications, recent studies demonstrated that MGO accumulated in vascular tissues of hypertensive animals. We hypothesized that MGO could directly affect vas...

Full description

Bibliographic Details
Main Authors: Masashi Mukohda, Hideyuki Yamawaki, Hidemi Nomura, Muneyoshi Okada, Yukio Hara
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319312861