Simultaneous determination of asenapine and valproic acid in human plasma using LCâMS/MS: Application of the method to support pharmacokinetic study
Combination of asenapine with valproic acid received regulatory approval for acute treatment of schizophrenia and maniac episodes of bipolar disorders. A simple LCâMS/MS method was developed and validated for simultaneous quantification of asenapine and valproic acid in human plasma. Internal standa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013-12-01
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| Series: | Journal of Pharmaceutical Analysis |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177913000543 |